Researchers have shown that when skin is compressed, micropores form in the folds of the skin, through which the same amount of medicine can penetrate as through dozens of microneedles.
Scientists from Nanyang Technological University were inspired by a method of traditional Chinese medicine called tuyin massage, during which doctors rubIn the course of research, it was found that compression of the skin leads toto a short-term change in its structure with the formation of a pore diameter of 3 μm.
Tests have shown that six times more drugs can penetrate through these micropores than with conventional transdermal administration.In addition to being painless, this process allows the introduction of particles with a molecular weight of up to 20,000 tons.Dalton, which is 40 times more than usual, as well as monitor the rate of drug intake.The micropores disappear completely a day after they are formed.
Experiments have shown that the effectiveness of insulin administration by this method is similar to a medical patch with dozens of microneedles, and the ability to control the speed minimizes the risk of hypoglycemia.
Scientists plan to improve this method and one day save people who have to inject every day from using needles and piercing their skin.
Earlier we also reported on the development of a convenient blood pressure monitor in the form of a patch.
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