Researchers have synthesized a fusion protein that increases the effectiveness of T-lymphocytes in fighting cancer cells, literally energizing them.
The human immune system itself is practically unable toresist malignant tumors, since it is difficult for lymphocytes to destroy the tumor. Therefore, doctors have to stimulate them so that the patient’s body begins to fight cancer on its own. This method of therapy is effective, but only helps 20-30% of patients, since in the process of fighting cancer cells, lymphocytes quickly get tired andwear out.
For many years, researchers around the world have studiedways to improve immunotherapy. Recently, however, an international team of scientists led by bioengineers from the Federal Polytechnic School of Lausanne found a solution. They found that the interleukin-10-Fc fusion protein is able to interact with T-lymphocytes, giving them a boost of energy, as a result of which they reactivate and continue to fight cancer.
Mouse studies have shown that proteinsignificantly increases the effectiveness of adaptive immunotherapy. With its help, 90% of experimental rodents were able to get rid of cancer. The team also notes that interleukin-10-Fc has helped destroy larger tumors that are usually difficult to treat.
We also previously reported on the discovery of a protein that turns cancer cells into normal cells.
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