September 26, 2022

Bio dressing invented to accelerate the healing of broken bones

Bio dressing invented to accelerate the healing of broken bones

The researchers created a bandage thatcaptures and holds healing molecules at the site of a bone fracture, accelerating the natural healing process of tissues and reducing the time of complete recovery to three weeks.

In 2014, scientists discovered that a biomoleculeadenosine plays an important role in stimulating bone growth. When a bone is damaged or broken, the body naturally fills the area around the injury with these molecules, but they do not linger for a long time in one place and quickly collapse. In addition to participating in the process bone healing, adenosine performs many other important functions in the body, so only a local increase in its level is permissible.

To solve the problem, the biomedical team fromDuke University has developed a biomaterial dressing coated with borate molecules. When she wraps a broken bone, it captures and retains adenosine near the site of damage. The second version of the dressing they additionally covered with adenosine, which was gradually released. Since in both cases the healing molecules gradually decomposed, they did not disturb the natural balance and did not cause side effects.

Bio dressing invented to accelerate the healing of broken bones

Laboratory tests in mice showed that fora week, each type of processed dressings significantly improved the process of splicing. Three weeks later, healing was observed in all experimental subjects, but in those using adenosine bio-dressings, a better bone formation was observed, with a large volume of tissue and better vascularization.

Bio dressing invented to accelerate the healing of broken bones

Researchers say dressings canmade of biodegradable material for quick healing of fractures, or create a permanent option in which new adenosine can be administered to treat repeated injuries associated with aging or osteoporosis. In addition, they plan to develop a gel for external use.

Recently, we also reported on the creation of an intelligent bionic pacemaker, which makes the heart beat with a natural rhythm, increasing the efficiency of blood pumping.