Scientists synthesized mini-protein from spider venom, which relieves severe pain as effectively as morphine, without causing addiction and side effects.
Opioids are good at relieving pain, but theyuse is associated with various undesirable side effects and the risk of drug addiction, which creates a huge burden for society. However, a recent study by biologists from the University of Queensland showed that the protein in the tarantula poison Huwentoxin-IV is able to bind to pain receptors in the body.
Using a three-stepdrug design system, scientistsaltered this substance to improve the degree of its interaction with specific pain receptors and cell membranes surrounding them. Tests in laboratory rats have confirmed its effectiveness and safety.
According to biologists, the results of the study will allow to develop an alternative method of treating pain without negative consequences and will help to reduce the dependence of many people on opioids.
We also previously reported the discovery of a protein that turns cancer cells into normal body tissues without additional treatment.
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